Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline American Airlines

The cheapest airline(s) flying from Greenville to San Diego is American Airlines.

  • American Airlines American Airlines
  • Delta Air Lines Delta Air Lines
  • United Airlines United Airlines
Cheapest Month June

Travel Period: June 2024 - May 2025

The cheapest month(s) to fly from Greenville to San Diego is June.

  • Jun 2024
  • Jul 2024
  • Aug 2024
  • Sep 2024
  • Oct 2024
  • Nov 2024
  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
Cheapest Day of the Week Wednesday

The cheapest day(s) of the week to fly from Greenville to San Diego is Wednesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday
Cheapest Time 5am

The cheapest time of the day to fly from Greenville to San Diego is in the early morning.

Early Morning 12:01am - 06:00am
Morning 6:01am - 12:00pm
Afternoon 12:01pm - 6:00pm
Evening 6:01pm to 12:00am
12am
6am
12pm
6pm

Flight Schedules

Last Updated: Thu, 2 May, 2024

  • Depart Earliest
    • Earliest
    • Latest
  • Arrive
    • Earliest
    • Latest
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  • Total Duration
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  • Availability
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  • 06:46 - 11:22
    GSP - SAN
  • 06:46 (GSP)Greenville/Spartanburg Airport
  • 11:22 (SAN)San Diego International Airport
  • United Airlines (UA 2445)Airbus
  • 7h 36m
  • Direct
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  • Airbus

Connecting Flights

  • 06:40 - 07:40
    GSP - ATL
    12:05 - 13:40
    ATL - SAN
  • 06:40 (GSP)Greenville/Spartanburg Airport
    12:05 (ATL)Atlanta Hartsfield-Jackson Intl Airport
  • 07:40 (ATL)Atlanta Hartsfield-Jackson Intl Airport
    13:40 (SAN)San Diego International Airport
  • Southwest Airlines (WN 222)Boeing 737 700
    Southwest Airlines (WN 6065)Boeing 737 700
  • 10h (4h 25m)
  • ATL Atlanta 4h 25m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 10:05 - 11:55
    STL - SAN
    06:45 - 07:45
    GSP - ATL
  • 10:05 (STL)St Louis Lambert Intl Airport
    06:45 (GSP)Greenville/Spartanburg Airport
  • 11:55 (SAN)San Diego International Airport
    07:45 (ATL)Atlanta Hartsfield-Jackson Intl Airport
  • Southwest Airlines (WN 4676)Boeing 737 800
    Southwest Airlines (WN 222)Boeing 737 700
  • 8h 10m (1h 35m)
  • SAN 1h 35m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 11:15 - 12:35
    HOU - SAN
    06:55 - 07:55
    GSP - ATL
  • 11:15 (HOU)Houston Hobby Airport
    06:55 (GSP)Greenville/Spartanburg Airport
  • 12:35 (SAN)San Diego International Airport
    07:55 (ATL)Atlanta Hartsfield-Jackson Intl Airport
  • Southwest Airlines (WN 5104)Boeing 737 800
    Southwest Airlines (WN 222)Boeing 737 700
  • 8h 40m (2h 10m)
  • SAN 2h 10m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 12:10 - 13:10
    AUS - SAN
    06:55 - 07:55
    GSP - ATL
  • 12:10 (AUS)Austin-Bergstrom International Airport
    06:55 (GSP)Greenville/Spartanburg Airport
  • 13:10 (SAN)San Diego International Airport
    07:55 (ATL)Atlanta Hartsfield-Jackson Intl Airport
  • Southwest Airlines (WN 4069)Boeing 737 700
    Southwest Airlines (WN 222)Boeing 737 700
  • 9h 15m (2h 50m)
  • SAN 2h 50m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 11:10 - 12:20
    PHX - SAN
    07:00 - 08:00
    GSP - ATL
  • 11:10 (PHX)Phoenix Sky Harbor Intl Airport
    07:00 (GSP)Greenville/Spartanburg Airport
  • 12:20 (SAN)San Diego International Airport
    08:00 (ATL)Atlanta Hartsfield-Jackson Intl Airport
  • Southwest Airlines (WN 3966)Boeing 737 800
    Southwest Airlines (WN 222)Boeing 737 700
  • 8h 20m (1h 55m)
  • SAN 1h 55m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 15:30 - 16:45
    PHX - SAN
    11:00 - 12:25
    GSP - HOU
  • 15:30 (PHX)Phoenix Sky Harbor Intl Airport
    11:00 (GSP)Greenville/Spartanburg Airport
  • 16:45 (SAN)San Diego International Airport
    12:25 (HOU)Houston Hobby Airport
  • Southwest Airlines (WN 4129)Boeing 737 700
    Southwest Airlines (WN 2904)Boeing 737 700
  • 8h 45m (2h 20m)
  • SAN 2h 20m
    • -
    • -
    • -
    • -
    • -
    • -
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  • 16:15 - 17:25
    PHX - SAN
    11:00 - 12:30
    GSP - BWI
  • 16:15 (PHX)Phoenix Sky Harbor Intl Airport
    11:00 (GSP)Greenville/Spartanburg Airport
  • 17:25 (SAN)San Diego International Airport
    12:30 (BWI)Baltimore Washington International Airport
  • Southwest Airlines (WN 1844)Boeing 737 800
    Southwest Airlines (WN 2809)Boeing 737 Max 8 Passenger
  • 9h 25m (1h 50m)
  • SAN 1h 50m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 12:10 - 13:35
    GSP - HOU
    14:25 - 15:50
    HOU - SAN
  • 12:10 (GSP)Greenville/Spartanburg Airport
    14:25 (HOU)Houston Hobby Airport
  • 13:35 (HOU)Houston Hobby Airport
    15:50 (SAN)San Diego International Airport
  • Southwest Airlines (WN 2904)Boeing 737 700
    Southwest Airlines (WN 5104)Boeing 737 800
  • 6h 40m (50m)
  • HOU Houston 50m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 16:55 - 18:00
    AUS - SAN
    12:30 - 13:25
    GSP - ATL
  • 16:55 (AUS)Austin-Bergstrom International Airport
    12:30 (GSP)Greenville/Spartanburg Airport
  • 18:00 (SAN)San Diego International Airport
    13:25 (ATL)Atlanta Hartsfield-Jackson Intl Airport
  • Southwest Airlines (WN 2139)Boeing 737 700
    Southwest Airlines (WN 223)Boeing 737 800
  • 8h 30m (2h 05m)
  • SAN 2h 05m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 17:10 - 18:15
    AUS - SAN
    12:35 - 13:40
    GSP - ATL
  • 17:10 (AUS)Austin-Bergstrom International Airport
    12:35 (GSP)Greenville/Spartanburg Airport
  • 18:15 (SAN)San Diego International Airport
    13:40 (ATL)Atlanta Hartsfield-Jackson Intl Airport
  • Southwest Airlines (WN 2139)Boeing 737 700
    Southwest Airlines (WN 223)Boeing 737 800
  • 8h 40m (2h 05m)
  • SAN 2h 05m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 16:20 - 17:45
    GSP - BWI
    19:45 - 22:15
    BWI - SAN
  • 16:20 (GSP)Greenville/Spartanburg Airport
    19:45 (BWI)Baltimore Washington International Airport
  • 17:45 (BWI)Baltimore Washington International Airport
    22:15 (SAN)San Diego International Airport
  • Southwest Airlines (WN 2809)Boeing 737 700
    Southwest Airlines (WN 4076)Boeing 737 Max 8 Passenger
  • 8h 55m (2h)
  • BWI Baltimore 2h
    • M
    • -
    • -
    • T
    • F
    • -
    • -
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What’s the fastest flight time from Greenville to San Diego?

The fastest flight time for direct flights from Greenville to San Diego is 7 hours 36 minutes. Check latest flight schedules & prices on Wego.

How far is San Diego from Greenville?

The flight distance between Greenville and San Diego is 3205km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 06:40. The last flight of the day departs at 06:40. See the full list of flight times on Wego.

How many airlines offer direct flights from Greenville to San Diego?

There are 1 airlines that offer direct flights from Greenville to San Diego. Find out the list of airlines on Wego.